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Department of Chemistry and Biochemistry

Dr. Nick Flynn

Dr. Flynn

Assistant Professor of Biochemistry
(325) 942-2181, Ext. 250
Honors Program Director
E-mail: nick.flynn@angelo.edu

Education:

NIH Postdoctoral Fellowship, Columbia Medical School (1997-1998)
Ph.D., Texas A&M University (Nutritional Biochemistry)
B.S., Texas A&M University (Biochemistry, 1992)

Courses taught: CHEM 1411, CHEM 1412, CHEM 4331, CHEM 4332, CHEM 6383

Courses taught in the Honors Program: HONR 1202, HONR 3281, HONR 4181

Dr. Flynn's research philosophy

Research interests:

My research interests include the study of amino acid metabolism in various organisms, the production of acrylamide and other compounds in food processing methods, intestinal development in relation to amino acid metabolism, and metabolic differences between individuals.

I am also interested in chemical education. In particular I am interested in science outreach programs and the usage of undergraduate students to develop course materials and pedagogy.

First Author Publications

  1. Flynn, NE. Science Days: An Interdisciplinary Outreach Program (2005) 82: 1483-1485. J. Chem. Ed.
  2. Flynn, NE, Meininger, CJ, Haynes, TE, Shi, Wenjuan and Wu, G. (2004) Book Chapter: “Mechanisms for dietary regulation of nitric oxide synthesis in mammals.” Book Title: “Nutrients and Cell Signaling” Publisher: Marcell Dekker.
  3. Flynn, NE and Wu, G. (2003) Invited review. Regulation of intestinal amino acid metabolism by glucocorticoids. Recent Res. Develop. Physiol. 1: 169-178.
  4. Flynn, NE, Meininger, C.J., Haynes, T.E., Wu, G. (2002) The metabolic basis of arginine nutrition and pharmacotherapy. Biomedicine & Pharmacotherapy Biomed. Pharmacother. 56: 427-438.
  5. Flynn, N.E., Knabe, D.A., Mallick, B.K. and Wu, G. (2000) Postnatal Changes of Plasma Amino Acids in Suckling Pigs J. Anim. Sci. 78(9): 2369-75
  6. Flynn, N.E., Meininger, C.J., Kelly, K., Ing, N.H., Morris, S.M., Wu, G. (1999) Glucocorticoids mediate the enhanced expression of intestinal type II arginase and argininosuccinate lyase in postweaning pigs. J. Nutrition 129 (4): 799-803
  7. Flynn, N.E. and Wu, G. (1997) Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs. J. Nutr. 127: 732-737.

Undergraduate student publications

  1. Loomis, L and Flynn, NE (2006) Determining glucocorticoid receptor activity in American dietary components using S-gal as a novel reporter substrate. Journal of Undergraduate Chemistry Research. 3: 111-114.
  2. Wagner, J and Flynn, NE (2003) Comparison of acrylamide content in corn and potato snack chips via High Performance Liquid Chromatography. Journal of Undergraduate Chemistry Research. 3: 87-90.

Submitted Publications

  1. Flynn, NE, Patyrak, M and Seely, J. (2006) Saccharomyces cerevisae and Candida albicans metabolize glycine through different pathways. (Submitted to Eukaryotic Cell)

Recent Presentations

  1. Determining Glucocorticoid Activity in American Dietary Components (2006). National ACS meeting (Atlanta, GA); Loomis, L and Flynn, NE.
  2. Saccharomyces cerevisae and Candida albicans metabolize arginine and glutamine differently. (2005). National ACS meeting (Anaheim, CA); Flynn, NE, Seely, J, Patyrak, M and Martin, Z.
  3. Correlation of vital statistics to glucose metabolism: A pilot study (2004). Carr Research Scholar symposia (San Angelo, TX; ASU). Flynn, NE and Hinojosa WD.
  4. Glycine metabolism in C. Albicans and S. Cerevisae (2004). National ACS meeting (Anaheim, CA); Flynn, NE, Patyrak, M and Seely, J.
  5. Science Days: A collaborative science outreach project (2004). National ACS meeting (Anaheim, CA); Lowther, E and Flynn, NE.
  6. Comparison of Acrylamide Content in Snack Chips via High Performance Liquid Chromatography. (2004) National ACS meeting (Anaheim, CA); Rattanasavanh, S, Wagner, J, Flynn, NE.
  7. Comparison of Acrylamide Content in Snack Chips (2004) Texas Academy of Sciences (Kerrville, TX); Rattanasavanh, S, Wagner, J, Flynn, NE.
  8. Comparison of Acrylamide Content in Snack Chips via HPLC. (2003) Texas Tech Health Science Center, Undergraduate Poster Competition. Wagner, J and Flynn, NE.
  9. The history and rules of rugby. (2002) Faculty luncheon lecture series (San Angelo, TX; ASU)
  10. Validation of a method to determine glycine metabolism in yeast using C13-glycine. (2001) Southwest Regional Meeting of ACS (San Antonio, TX); Undergraduate poster-Patyrak, M. and Flynn, NE.
  11. Flynn, N.E. (1999) The biochemistry of diet, nutrition and exercise. Faculty luncheon lecture series and community organizations (San Angelo, TX; ASU).

Second Author Publications

  1. Wu G., Flynn N.E.; Knabe D.A. and Jaeger, L.A. (2000) A cortisol surge mediates the enhanced polyamine synthesis in porcine enterocytes during weaning. Am J Physiol Regul Integr Comp Physiol. 279(2): R554-9.
  2. Wu, G., Flynn, N.E., Knabe, D.A. (2000) Enhanced intestinal synthesis of polyamines from proline in cortisol-treated piglets. Am. J. Physiol. Aug; 279(2): E395-402
  3. Wu G, Flynn NE, Flynn SP, Jolly CA, Davis PK (1999) Dietary protein or arginine deficiency impairs constitutive and inducible nitric oxide synthesis by young rats. J. Nutr. 129(7): 1347-54.
  4. Wu, G., Davis, P.K., Flynn, N.E., Knabe, D.A. and Davidson, J.T. (1997) Endogenous synthesis of arginine plays an important role in maintaining arginine homeostasis in postweaning growing pigs. J. Nutr. 127: 2342-2349.