Diabetes Research Lab
The ASU Diabetes Research Lab conducts various basic science and clinical research projects. The primary focus is to investigate the effects of biophysical agents including heat therapy, electrical stimulation, infrared therapy, and therapeutic ultrasound on diabetes.
The Diabetes Research Lab is located in the Ben Kelly Center for Human Performance, room 141.
- The effects of heat therapy on people with type 2 diabetes
- The relationship between balance, gait performance, and fall risk in people with diabetic peripheral neuropathy
- The effects of low-level infrared therapy on insulin resistance in skeletal muscles
- The effects of low-level laser therapy on insulin secretion in pancreatic islet cells
- Moore, K., Sterling, K., VanHoose, L.D., Curtis, D. A., Huang, H-H. (2021) The Prevalence of Wound Management Physical Therapist Practice in the State of Texas, Physiotherapy Theory and Practice, (Online ahead of print)
- Huang, H-H., Gathright, B., Holik, R., Iverson, H., Saville, E., Curtis, D. A. (2021) Active Video Game Program for People with Type 2 Diabetes- A Pilot Study, Applied Sciences, 11(22): 11046.
- Curtis, D. A., Nicks, K., Huang, H-H. (2021) Patient Deception in Healthcare: Longitudinal Effects of Different Educational Interventions, North American Journal of Psychology, 23(1):77-94.
- Brown, J., Huang, H-H., Brown, Ji. (2020) A West Texas County Food Insecurity Survey Findings, Journal of Public Health Issues and Practices, 4(2):169.
- Villers, J.F., Burch, J., Scheller, M., Huang, H-H. (2020) Physical therapy prehabilitation on a reverse total shoulder replacement candidate: a case study, Journal of Physical Therapy Science, 32(2):197-205.
- Moore, K., Autumn, H., VanHoose, L.D., Huang, H-H. (2020) Current Wound Care Education in Entry-Level Doctor of Physical Therapy Curricula, Advances in Skin & Wound Care, 33(1):47–52.
- Ahmed, S.S., Giardina, M., Nicks, K., Huang, H-H., (2020) Physical therapy examination and management of a 48-year-old male with vertigo and cervicalgia secondary to Chiari malformation. Physiotherapy Theory and Practice, 36(9):1056-1067
- Curtis, D. A., Huang, H-H., Nicks, K., (2018) Patient Deception in Health Care: Physical Therapy Education, Beliefs, and Attitudes, International Journal of Health Sciences Education, 5(1).
- Huang, H-H., Harrington, S., Stehno-Bittel, L., (2018) The Flaws and Future of Islet Volume Measurements. Cell Transplantation, 27(7):1017-1026
- Buchanan, A., Wilkerson, K., Huang, H-H., (2018) Physical therapy for transverse myelitis: a case report. Journal of Novel Physiotherapy and Rehabilitation, 2:015-021
- Huang, H-H., Cook, L., Harrison, j., O’Keefe, N., Schultz, K., Curtis, D. A., (2017) Exercise by playing active video gaming in overweight and obese children. Journal of Physical Therapy and Sports Medicine, 1(1):25-31.
- Huang, H-H., Weise, S., Ko, M-S., Hansen, T., Johnson, A., McCluskey, C., (2017) Effects of Motor-level Electrical Stimulations on Postprandial Glucose Levels in Non-Diabetic Young Individuals. Journal of Novel Physiotherapy and Physical Rehabilitation, 4(1):027-032
- Huang, H-H., Stehno-Bittel, L., (2015) Differences in insulin biosynthesis pathway between small and large islets do not correspond to insulin secretion. Islet,7(5):e1129097.
- Ramachandran, K., Huang, H-H., Stehno-Bittel, L., (2015) A simple method to replace islet equivalents for volume quantification of human islets. Cell Transplantation, 24(7):1183-94.
- Rawal, S., Huang, H-H., Novikova, L., Hamedi, T., Smirnova, I.V., Stehno-Bittel, L., (2013) Effect of exercise on pancreatic islets in zucker diabetic fatty rats. J Diabetes Metab, S10(007).
- Ramachandran, K., Williams, S.J., Huang, H-H., Novikova, L., Stehno-Bittel, L., (2013) Engineering islets for improved performance by optimized reaggregation in a micro-mold. Tissue Engineering, 19(5-6):604-12.
- Farhat, B., Almelkar, A., Ramachandran, K., Williams, S.J., Huang, H-H., Zamierowksi, D., Novikova, L., Stehno-Bittel, L., (2013) Small human islets comprised of more β-cells with higher insulin content than large islets. Islets, 5(2):87-94.
- Huang, H-H., Ramachandran, K., Stehno-Bittel, L., (2012) A replacement for islet equivalents with improved reliability and validity. Acta Diabetol, 50(5):687-96.
- Wang, W., Guo, Y., Xu, M., Huang, H-H., Novikova, L., Larade, K., Jiang Z-G., Thayer T.C., Forntera J.R., Aires D., Ding H., Turk, J., Mathews C.E., Bunn H.F., Stehno-Bittel, L., Zhu, H. (2011) Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells. Biochimica et Biophysica Acta- Molecular Basis of Disease, 1812(11):1532-41.
- Huang, H-H., Novikova, L., Williams, S.J., Smirnova, I.V., Stehno-Bittel, L., (2011) Low insulin content of large islet population is present in situ and in isolated islets. Islets, 3(1):6-13. (Image is used on the cover of the journal)
- Huang, H-H., Farmer, K., Windscheffel, J., Mason, K., Power, M., Wright, D., Stehno-Bittel, L., (2011) Exercise increases insulin content and basal secretion in pancreatic islets in type 1 diabetic mice. Experimental Diabetes Research, 2011:481427 (Figure is used in the review article by Dr. Narendran at the University of Birmingham in UK as a strong evidence of exercise effect on beta-cells)
- Williams, S.J., Huang, H-H., Kover, K., Moore, W., Berkland, C., Singh, M., Smirnova, I.V., MacGregor, R., Stehno-Bittel, L., (2010) Reduction of diffusion barriers in isolated rat islets improves survival, but not insulin secretion or transplantation outcome. Organogenesis, 6(2):115-24.
PI
- $15,000 total direct costs
- “The Investigation of the Effects of Therapeutic Electrical Stimulation on People with Type 2 Diabetes.”
- 2016-2017, Faculty Research Enhancement Program Award, Angelo State University
PI
- $2,200 total direct costs
- “Comparison of electrical stimulation parameters in postprandial skeletal muscle glucose uptake.”
- 2015-2016, Texas Physical Therapy Foundation
PI
- $15,000 total direct costs
- “The Investigation of the Effect of Therapeutic Pulsed Ultrasound on Controlling Blood Sugar in Diabetes.”
- 2015-2016, Faculty Research Enhancement Program Award, Angelo State University
Co-PI
- $5,000 total direct costs
- “The Investigation of the Effects of Animal-assisted Therapy on Post-stroke Rehabilitation.”
- 2014-2015, Faculty Research Enhancement Program Award, Angelo State University
PI
- $10,000 total direct costs
- “The Investigation of the Potential of Infrared Light Therapy in Controlling Blood Sugar in Diabetes.”
- 2013-2014, Faculty Research Enhancement Program Award, Angelo State University
PI
- $10,307 total direct costs
- “Start-up Funds to Establish a Cell-Culture Laboratory in Physical Therapy.”
- 2012-2013, Faculty Research Enhancement Program Award, Angelo State University